I am trying to find out what is the major difference between a chronic and acute fissure???? Thank you!

An acute fissure is a fissure in it's early stages, it can be healed successfully at this stage through diet and/or creams, most docs would call a fissure chronic if you've had it for 6 weeks or longer and had no success with dietary changes etc, also, a chronic fissure builds up scar tissue over time through constant partial healing followed by a re-tear, this in turn makes it very difficult to heal and surgery is usually the only solution.

Thank you Steve!

A chronic fissure coughs all the time, an acute fissure is really cute.
All kidding asside chronic fissures dont heal after six weeks.