Hi Everyone, well after a week of taking Antibiotics for a bacterial infection, I'm in Fissure hell. My stomach has been upset by the weeks course, and my BMs have varied between Bristol 4 and 6-7. My delicate bottom can't take this, and today after 2 horrible BM's I'm sore, burning and both Fissure sites are painful. I've used Nitro and some metanium. I've also been taking prebiotics just so all of my good bacteria isn't killed off! I'd got everything under control again, so I'm very annoyed at this horrible set back. Any ideas on what I can it's to calm it down? My bathroom already looks like a pharmacy! Nothing is soothing the burn! Help. After nearly 2 years of this hell, I just want to give up!!!