CRS R.L. Nelson (Rick Nelson) conducted and published a systematic review and meta-analysis of all published treatments for anal fissure that have been studied in randomised controlled trials. In this podcast he describes his work and its results. While his replies to questions are interesting, I was struck by the number of times he mentions the "confusion" that surrounds much of the research into AF - it seems that reliable evidence relating to treatments and outcomes in AF is hard to obtain.
https://www.podomatic.com/podcasts/schoolofsurgery/episodes/2017-09-16T03_56_40-07_00