Dear Tubby

, you are more than welcome

Since all of those creams (Nitro, Nifedipamine and I suppose other "compounds") have vaseline as a base - I see no reason why pure vaseline would be any different

. Vaseline is completely "inert" which means that it is not absorbed by skin or mucous membranes. Regarding hygiene, same way - if you used any other cream inside it is the same thing. You will poop it out anyway LOL as soon as you go to the bathroom : ) ! I am sorry that they changed Preparation -H formula, originally it was mostly fish oil and was great as natural lubricant (sigh). Maybe we should start our own business and start manufacturing fissure friendly suppositories

!!!!??? Small size, slippery and completely mild and with natural oils and herbs !!!!
BTW: I discovered that Aloe gel is great lubricant for insertion of suppositories ! I also put mixture of aloe, vit. E, vit.A, and baby A+D cream on a tip of my suppository and it glides in smoothly and also brings "in" those extra vitamins !
All the best :sprinkleheart:
PS: You used so much creams because you tried to heal the fissure :truebud: dear buddy and it is not a short or small task XOXO I used Nitro 0.4 (!!!!) AND Nifedapine in combo LOL - so don't be angry at yourself - you intentions were the best and everybody reacts differently to meds!