Soreguy wrote:From what I have gathered on the drug class, Benzos are more damaging and have a much harsher withdrawal, where opiods are much more addictive, less damaging and dont have much of a come down at all.
I actually agree with the striked out part, except I wouldn't say benzos are necessarily more damaging than opiates or vice-versa. I think the jury is still out on that ... most benzos create more active metabolites, but opiates are typically combined with APAP (the only formulation available under normal circumstances here in the States) which is very hepatoxic.
The rest is pretty much 100% right on. For most people, opiates are more addictive, but withdrawal is INFINITELY easier in the long run. And it's not even close. In the short term, opiate withdrawal is hell on earth, but you just need to ride it out. That's it. It will be uncomfortable, and you will feel sick, but as long as you tough it out, you'll be fine once the drug clears your system, which isn't very long for most opiates. A couple of weeks max. Benzos, on the other hand, can have VERY long half lives, and are actually dangerous -- not just uncomfortable -- to withdraw from. The main risk in the short term is seizures, and in the long term, it's the possibility of protracted benzodiazepine withdrawal syndrome.
Anyone who has withdrawn from drugs, especially multiple drugs, will tell you that benzo withdrawal is THE ABSOLUTE WORST of them all. No question whatsoever. It takes the longest, comes with much more deeply engrained physical dependency, and is MUCH less predictable (this last bit is what makes it so sinister). And the other worst parts: you can get addicted very quickly and without knowing it, and you can suffer tolerance withdrawals even when you haven't reduced your dosage. Benzo withdrawal is PURE EVIL -- I just can't stress this enough -- and should be avoided at all costs. The way benzos actually modulate the GABA neurotransmitter system is very poorly understood, and for many people (just look on Benzo Buddies or the other countless benzo support groups out there) the brain chemistry changes are essentially permanent, meaning they wind up having to take GABA modulators their entire lives (some switch to gabapentin after coming off benzos for example).
P.S.
I'm by no means a completely anti-drug guy a la Tom Cruise. I think every drug has its usage case, and am actually a fan of some recreational drugs (i.e., marijuana for instance). But IMO benzos are often taken lightly when the effects can be potentially devastating. Anyone who decides to start these should be absolutely certain that they're prepared for the possibility of the worst case. (On top of that, Valium is generally recognized as having greatest efficacy for skeletal muscle relaxation, not smooth muscle, and there's no consensus on its effectiveness for smooth muscle spasms.)
Ok so that's my benzo doom 'n gloom rant. Just be careful if you're hopping on the benzo train, that's all. And yes, to be perfectly fair: the converse is that many people take them and have no problems at all. As with anything else, there is variance. But for these particular drugs, there are enough people out there who have really bad times with them that IMO fair warning is warranted.
P.P.S.
For the original poster: methocarbomal is another skeletal muscle relaxant which (IMO only) probably won't be too useful for fissures. I've taken it before and it constipated me and also seemed to have no noticeable effect. Your mileage may vary, of course, but don't be shocked if it doesn't do anything. I've never personally heard of buscopan but from the name it sounds like it might be one of the belladonna alkaloids? If so those are often used for treating intestinal spasms, usually in combination with other antispasmodics. Look that one up, if it's a belladonna alkaloid or otherwise comes from the belladonna plant family then odds are it's used more for IBS than for fissures.