However, the minority of proctalgia patients affected by unspecified functional anorectal pain are still left without a satisfactory treatment option. In this regard, depression and anxiety are both frequently reported in non-responsive proctalgia patients[6,10]. Brain processing of pain may be altered in functional gastrointestinal disorders, but data in proctalgia patients are lacking[22]. In addition, no trial has actually evaluated the effect of either psychotherapy intervention or psychotropic drugs in proctalgia patients. Finally, there is no evidence that surgery can help these severely disabled patients. Invasive interventions should be avoided in the absence of a clearer etiologic understanding of non-responsive proctalgia patients.
Although I'm not severely disabled and can cope with day-to-day life in spite of the pain and discomfort, I have searched in vain for anything that might might explain my proctalgia and ongoing perineal inflammation, which has lasted for several years and shows no signs of going away. No GP or CRS I have consulted has been able to offer such an explanation, apart from an initial diagnosis of AF, which healed long ago.
There seem to be some areas of colorectal disorder and pelvic floor dysfunction where doctors either don't have answers or are still in quest of them, and I'm left wondering why this should be so.