when i used it,it sometimes gave me the "urge" to go,never diahrea though,i was on the .05% then it was boosted up to the 2%,that stuff was powerful,but after time the headaches got less,like i was getting used to it or something.it really did loosen things up down there,i was told 2times a day,but me being the self appointed dr that i am

,decided it wopuld be better if i used it like 5 times a day,i figured the looser,longer..the faster it'd heal! dont know if it worked,but when i went to get more they were like "already"..i told them i'd been using it as chapstik for my lips,they didnt think it was funny though....