Gonyautoxin Injection

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Gonyautoxin Injection

Postby Carolineandy1 » 26 Sep 2013, 06:10

Hi was reading the report on the Innovations in chronic anal fissure treatment and other reports on it and it says that the Gonyautoxin injection gives a 100% success rate. I know clinical trials can take years and years but has anybody come across this before? Anybody know if it is available for use as a viable treatment option yet? Or even when it will? DESPERATE!!!
Fissure +9 Years
GTN mixed results
LIS 18.9.14
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Re: Gonyautoxin Injection

Postby Scientist2516 » 26 Sep 2013, 11:24

Hi Carolineandy. I've seen this too. There are two papers on it, both from the same group, in 2005 and 2007 if I recall. They are in S. America - Chile?, not the USA.
There has been nothing since.
I have to think that some unacceptable side-effects occurred or that somehow the treatment didn't live up to its early promise. Otherwise there would be more studies by now.
I'm seeing a CRS today, and I can ask him if he knows anything about it.
Nifedipine/lidocaine, no help
Diltiazem, effective, but caused major rash
Nitroglycerine, effective.
Topical estrogen for final healing.
Gentle heat to bottom - pain relief, muscle relaxant
Kondremul mineral oil
Time - lots of time.
Status - Healed!
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Re: Gonyautoxin Injection

Postby Carolineandy1 » 26 Sep 2013, 13:06

Oh yes that would be good to see if he has some up to date information. Good luck with your appointment today x
Fissure +9 Years
GTN mixed results
LIS 18.9.14
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Re: Gonyautoxin Injection

Postby Scientist2516 » 26 Sep 2013, 15:32

Thanks - the appointment went well - I'm going to write about it soon.

He had never heard of gonyautoxin. My suspicion is that it was something that seemed brilliant that just didn't stand the test of time.
Nifedipine/lidocaine, no help
Diltiazem, effective, but caused major rash
Nitroglycerine, effective.
Topical estrogen for final healing.
Gentle heat to bottom - pain relief, muscle relaxant
Kondremul mineral oil
Time - lots of time.
Status - Healed!
User avatar
Scientist2516
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Re: Gonyautoxin Injection

Postby Carolineandy1 » 26 Sep 2013, 15:49

Good I am pleased for you that it went well. Looking forward to reading about it soon.

Shame about the gonyautoxin,it sounded like a miracle cure that many of us would jump at.
Fissure +9 Years
GTN mixed results
LIS 18.9.14
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Carolineandy1
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Posts: 36
Topics: 2
Joined: 24 Sep 2013, 08:55
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