I have had an anal fissure for 5 years, basically have been using nifedipine since 2006. As long as I stay on the nifedipine my fissure stay about 90% healed (No bleeding, spasms etc) I do get some pain sometimes if I have a hard poop or some diarrhea! Although the hard poop is much worse then the diarrhea! Yikes!
Anyway the specialist I am seeing says I can use the nifedipine ointment for as long as I want without any side effects. He thinks surgery for me is not the right option because of the risk of leakage (he says that there is a 45% percent chance of this that is not made known to most patients who have had LIS surgery)
He says the trick to keeping this under control is intake 35 grams of fiber each day (to keep bowel pressure to a minimum and stools soft etc) and use the ointment properly! Most people he says do not use the ointments correctly... he says you need to get the ointment as far as you can stick your finger in your butt! If you get it on the fissure, even better because it will absorb right into the opening of the fissure and into the bloodstream etc
My other secrets are too never, EVER use toilet paper and always use baby wipes and a butt cleansing spray to keep you butt clean after BM's. I sometimes will take a shower after if I can and then add some butt moisturizer as well :)
I can live a normal life so far, yes I do have some pain but it is bearable for now.
I just don't trust Botox as of yet and think the ointment can do the same job.
As for LIS, I just want to avoid surgery unless I really have too... why risk leakage and possible infections. They are cutting you open so there is risks involved! If I could not live a normal life, then that would be a different story... If LIS meant relief then I am all for it, but only as a last resort.
Hope this helps and I hope they come up with something new in the future that will bring relief to all who suffer from this little beast!