I too had a breakdown... But with the kind support from people on this forum, and my Family and friends, i did crawl out of the black hole i was in.I took Sertraline AD'S too, which i still currently take. They help reduce the Anxiety and stress i suffer from this Fissure hell. I didn't want to get out of bed, and i cried and cried for hours with the pain. Prior to Botox(which i had 10 weeks ago), i was a total wreck.It is so good to talk to people who understand the pain and agony these monsters cause.My poor sis in law is also suffering, she has 4 Fissures and growths. We often have a bum rant over the telephone, and we do feel a lot better after this!!! I hope that you can reach a decision soon on what to do.Please don't give up hope, there will be a solution...... If you look at my avatar, it just represents how i feel, just like i have a bag over my head, and i cannot take it off until these Fissures leave forever!!!