Whoa ok. So Kim, I think I *just now* figured out how to properly apply the nitro. Your earlier post was key. Remember how you suggested I wipe a bit after applying it to try to gauge how much actually got in? Well, I did just that, and noticed that a lot of it was on the tissue. I then realized two things:
(1) I don't think I was properly filling the syringe before. I thought I was getting a lot of nitro in the syringe, but I was actually drawing only a little ointment and a lot of air. In order to properly fill the syringe, I have to move the tip around while filling it so it's always pulling in ointment and doesn't accidentally pull in any air. Seems obvious but I'm not real used to using these things so this bit escaped me until now.
(2) I don't think my aim was very good before. I was trying to put the syringe into the anus while standing up, but that makes the "target" kind of hard to find. Lying down on my side makes it easier to locate where the syringe ought to go.
So what I did just now is fill the syringe without air pockets, laid on my side, made sure the tip of the syringe really is in the anus, and then gave it a gentle push. As soon as I squeezed it, I felt a sharp sting (made me jump instantly!) inside the anus and immediately got the throbbing nitro headache. Some of the ointment still ended up outside the anus, but the sensation this time was definitely different (much more of a sharp stinging feeling around the site of application) and the side effects came on much faster. I'm not sure if that's because more of the nitro found its mark (hopefully yes), or just because I had more rawness in there due to the bad BMs today, though. It's too bad my physician didn't give me better instructions so I could skip the last full week of trial and error, but good looking out on your earlier suggestion!